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How the Liver Works

This section describes the basic functions of the liver.

The Liver

Anatomy of the Liver

The Liver Up Close

Digestive Function of the Liver

Circulatory Function of the Liver
How Liver Cancer Develops

This section describes the basic development of cancer in the body and cancer as it spreads to the liver.

Liver Cancer

Understanding Cancer

Carcinogenesis

Growth of Cancer
How Liver Cancer Affects the Body

This section describes the basic symptoms of liver cancer.

Detecting Cancer


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Growth of Cancer

A small tumor no larger than 1 millimeter in diameter can sustain itself in such a manner indefinitely. But it cannot grow any larger unless the tumor itself begins to generate a network of blood vessels to help supply additional nutrients.

A clinically detectable tumor is about 1 gram in weight and made up of at least 1 billion cells.

Metastatic tumors form when large progressive tumors shed tumor cells. These tumor cells must be able to grow and function apart from the primary tumor.

Metastatic tumor cells move throughout the body, usually through the circulatory system or the lymphatic system.

Metastatic tumor cells often lodge in a blood capillary, where they may or may not grow. The tumor cells that actually grow are somehow more suited to the new location.

Metastatic tumor cells tend to mutate more quickly than normal cells, giving them a greater ability to adapt to their environment as well as a greater ability to resist therapy.

Metastatic tumor cells are more likely to infect places they can easily reach. Because the liver is close to or actually connected to several significant organs, and because the liver plays an important role in blood circulation by acting as a filter, metastatic liver cancer occurs in over 75% of all terminal cancer patients.



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