Growth of Cancer
A small tumor no
larger than 1 millimeter in diameter can sustain itself in such a
manner indefinitely. But it cannot grow any larger unless the tumor
itself begins to generate a network of blood vessels to help supply
additional nutrients.
A clinically detectable tumor is about 1 gram in weight and made up
of at least 1 billion cells.
Metastatic tumors
form when large progressive tumors shed tumor cells. These tumor cells
must be able to grow and function apart from the primary tumor.
Metastatic tumor cells move throughout the body, usually through
the circulatory
system or the lymphatic system.
Metastatic tumor cells often lodge in a blood capillary, where
they may or may not grow. The tumor cells that actually grow are
somehow more suited to the new location.
Metastatic tumor cells tend to mutate more quickly than normal
cells, giving them a greater ability to adapt to their environment as
well as a greater ability to resist therapy.
Metastatic tumor cells are more likely to infect places they can
easily reach. Because the liver is close to or actually connected to
several significant organs, and because the liver plays an important
role in blood circulation by acting as a filter, metastatic liver
cancer occurs in over 75% of all terminal cancer patients.
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